Friday, March 11, 2011

In the treatment of diabetes medicine is insulin?

Diabetes this noun everyone heard many times before. Western medicine tube diabetes called sweetness of urine, then on the doctor of traditional Chinese medicine, is called XiaoKeBing tube diabetes rot plus vexed thirst. Diabetes can be divided into two categories, one kind reason not too clear, we call primary diabetes, Another type of diabetes has its special etiology, such as pancreatic diseases can cause insulin secretion fits, do not come out, or by other endocrine causes against of the hormone insulin secretion too much; etc. This belong to the category of secondary diabetes.
Although the primary diabetes the etiology and pathogenesis is not yet completely clear, but at present, to say the least, diabetes basic for two reasons: first is the genetic factors, i.e. diabetes is have transmissibility, heredity is easier diabetes genes. If somebody thinks, insulin-dependent diabetes mellitus, genetic is islet prone to autoimmune destroy the genes; For niddm, generally considered a gene genetic, genetic is prone to obesity and insulin resistance and insulin secretion, shortage of genes. But, if only a genetic predisposition to the innate factors, not diabetes, but it needs to be acquired factors, namely environmental factors, this is the second factor, diabetes in the prevention of diabetes is also more notable factors, including heat absorb too much, activity decline, obesity, smoking and psychological stress, etc. These two factors long-term work together, make the person had diabetes.
The clinical manifestations of diabetes probably included two sides, one is high, the more blood sugar diabetes caused a few articles, eat more, drink more, micturition, weight loss. Another is complications caused by symptoms such as diabetic nephropathy, retinopathy, etc.
Insulin resistance refers to insulin stimulative airframe of the glucose ability to drop, in order to maintain normal blood sugar, islet B - compensatory sex cells secrete insulin, make insulin increases by, hyperinsulinemia.
Researchers have adopted the genetic testing method, in view of more than 200 cases of type 2 diabetes patients observation, discover the insulin resistance is directly cause of coronary heart disease, coronary heart disease risk factors and increase the culprit one. Because insulin resistance consequent plasma insulin, insulin original increased level of all can make type 2 diabetes patients plasma fibrinolytic enzyme original activation content inhibitory factor heighten, thereby affecting fibrinolysis system.
On this basis, the researchers established a simple and feasible tiny model packages for the determination of insulin resistance, screening reduced insulin resistance of drug, has the very high clinical popularize value. The researchers then for 75 cases hypertensie episodes of lacunar cerebral infarction risk factors for the patient's study, also found that insulin resistance is evoked such patients disease important factors. At the same time they also found insulin resistance and central model fat are concerned, and hypertensive patients have obvious islet B - cell function defects and insulin resistance, is developing into overt diabetes high-risk groups.
This series of research achievements for medicine clinical inspection, treatment, and prevention of insulin resistance caused serious illness provides theory basis and method. 

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